Age Span Fellowship in Multiple Sclerosis and Related Neuroinflammatory Disorders

Overview

The Age Span Fellowship in Multiple Sclerosis and Related Neuroinflammatory Disorders offers Clinical and Clinical and Research tracks for adult neurology and pediatric neurology trainees. 
The mission of this program is to provide integrated, longitudinal care from childhood to adulthood and accepts BOTH pediatric and adult neurology applicants.

Training occurs with our distinguished faculty and supported by advanced practice providers, pharmacists, research coordinators, and social worker. The Multiple Sclerosis and Related Disorders Clinic at Penn is recognized as a National MS Comprehensive Care Center of Excellence, integrating ancillary services to provide comprehensive care and availability of basic science, translational, and clinical research studies. 

The Age Span Program seamlessly integrates education, patient care, and research with the Children's Hospital of Philadelphia (CHOP) 

There are several opportunities to learn other neuroinflammatory conditions through the NMO and MOG-AD Disease Program, Undiagnosed White Matter Disorders Adult Neurogenetics Clinic, Neurosarcoidosis Clinic, and the Age-Span Women’s MS Program to develop well-rounded neuroinflammatory experts.

Fellowship Curriculum

  • Clinical Track: 1-year training in diagnosis and management of Multiple Sclerosis and related disorders including NMOSD, MOGAD, granulomatous disease, and neurological manifestations of systemic disease. By the end of training fellows are expected to demonstrate comfort in management of these disorders and complete a scholarly project in their area of interest.
    • Funding: Past & Current
      • National MS Society 
      • Transverse Myelitis Association
      • Industry Supported
      • This track can support International Graduates with a J-1 Visa
  • Research and Clinical Track: This is a combined research and clinical training fellowship track that will be tailored to the individual fellow’s training and career goals.
    • Funding: Mentor-based funding (Includes T32 and UE5 Mechanisms).
    • Potential Mentors:
      • Dr. Amit Bar-Or
      • Dr. Jennifer Orthmann-Murphy
      • Dr. Matthew Schindler
  • Additional Training Opportunities:
    • Clinical Research Certificate Program
    • Master of Science in Clinical Epidemiology (MSCE) Degree program in the Center for Clinical Epidemiology and Biostatistics (CCEB).
  • Didactics
    • Fellows Bootcamp Lecture Series: Introduction to MS and related neuroinflammatory disorders evaluation and management.
    • Monthly journal club addressing both clinical and research topics.
    • Monthly Invited Speaker Seminar: Highlights national and international leaders, covering research (basic and clinical) and clinical care. 
    • Bi-monthly case conferences in collaboration with CHOP
    • ACTRIMS Didactic Lecture Series (ACTRIMS LMS - ACTRIMS Didactic Lecture Series (mclms.net))

Application Process 

July 2027 Start Date

  • Clinical Track (Adult and Pediatric Candidates): SF Match
    • Submit: cover letter, curriculum vitae, three letters of recommendation and a professional photo.
    • Application Registration Opens: Monday, November 3, 2025.
    • Deadline for Completed Applications: Wednesday, February 4, 2026.
      • Will not accept applications after this date.
    • Interviews: Mid-February - April 2026.
    • Rank List Deadline: Wednesday, April 29, 2026, at 12PM PT
    • Match Results: Wednesday, May 6, 2026.
  • Research and Clinical Track (Adult and Pediatric Candidates): Not a Match
    • Submission Email: Please email the MSfellowshipdirectors@pennmedicine.upenn.edu to determine if post-doctoral training funding is available starting July 2027 and please include a proposed mentor.
    • Offers: Pending Mentor Funding.

Faculty

 Jennifer Orthmann-Murphy, MD, PhD
 Co-Director, Multiple Sclerosis and Related Disorders Fellowship







Rohini D. Samudralwar, MD
Co-Director, Multiple Sclerosis and Related Disorders Fellowship









 Sarah Hopkins, MD, MSPH
 Co-Director, Multiple Sclerosis and Related Disorders Fellowship 






  Amit Bar-Or, MD, FRCPC
  Director, Center for Neuroinflammation and   Neurotherapeutics
  Chief, Multiple Sclerosis Division 
  Melissa and Paul Anderson President's Distinguished Professor
  
  Faculty Profile




Joseph Berger, MD
Associate Chief of the Multiple Sclerosis Division
Professor of Neurology 

Faculty Profile




   

Clyde Markowitz, MD

Director, Multiple Sclerosis Center at Penn
Associate Professor of Neurology





Dina Jacobs, MD

Clinical Director, Multiple Sclerosis and Related Disorders Center
Associate Professor of Neurology

Faculty Profile


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Contact Information

Department of Neurology
3 Gates, Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104

Frances E. Jensen, MD, FACP
Chair of Neurology

Email PennNeuroFellowships@uphs.upenn.edu