Age Span Fellowship in Multiple Sclerosis and Related Disorders Program


The Multiple Sclerosis Fellowship program at Penn is designed to train physician-scientists within the field of MS, and is of 1-3 years’ duration. Participants complete clinical fellowship training and may also pursue post-doctoral training in a basic science laboratory or formal training in clinical research, including through the Master of Science in Clinical Epidemiology (MSCE) Degree program in the Center for Clinical Epidemiology and Biostatistics (CCEB). Our fellowship works in collaboration with the Children`s Hospital of Philadelphia. 

The Multiple Sclerosis Clinic at Penn is recognized as a National MS Comprehensive Care Center of Excellence
  • Neurological care at cutting edge 
  • Integration with ancillary services to provide comprehensive care including rehabilitation, physical and occupational therapy, urology, psychiatry, etc. 
  • Availability of research studies 
Funding Sources for the Fellowship Include:
  • National MS Society funding to the Division 
  • Transverse Myelitis Association funding 

History of the Multiple Sclerosis Division:

  • University of Pennsylvania MS Division was established in 1958 by Melvin Thorner, the second division in the U.S. created solely for MS care
  • 1963 – 1970 under the direction of Dr. Donald Silberberg
  • In 1970 under the leadership of Dr. Robert Lisak it became the first Comprehensive MS and Research center in the US.

Fellowship Curriculum

  • Fellows are introduced to MS and related neuroinflammatory disorders evaluation and management with a ‘boot camp’ lecture series at the start of fellowship
  • Fellows also have a monthly journal club addressing both clinical and research topics
  • There is a weekly Division-wide lecture series that covers research (basic and clinical) and clinical care 
  • There are bimonthly case conferences in collaboration with CHOP 
  • There is the option to pursue the MSCE program, which provides rigorous training in clinical research methodology through a combination of didactic coursework and supervised completion of a research project (Master’s Thesis). Core coursework for the MSCE degree includes the following:
    • Introductory Epidemiology (EP 510)
    • Introductory Biostatistics (EP 520)
    • Statistical Methods for Epidemiologic Research (EP 521)
    • Database Management for Clinical Epidemiology (EP 532)
    • Measurement of Health in Epidemiology (EP 542, or other health measurement course)
    • Issues in Research Protocol Development (EP 560)
    • Critical Appraisal of the Medical Literature (EP 570)
    • Tutorial in Epidemiologic Research (EP 610)


The Multiple Sclerosis Fellowship at the University of Pennsylvania was instrumental in reaching my goal of an academic career in MS. I trained under the mentorship and supervision of world experts in adult and pediatric MS in clinic and beyond. Penn’s MS fellowship is unique in many ways, not the least of which is the ability to train in adult and pediatric MS and gain valuable experience across the age spectrum. During my fellowship I also completed a Masters of Science in Clinical Epidemiology (MSCE) with training in epidemiology, biostatistics, database management and decision analysis. My research focuses on novel methods to capture and treat important and complex MS symptoms such as fatigue and cognitive dysfunction. I am also studying novel ways to capture subtle changes in disability and exploring new markers for progression and repair in patients with MS using the anterior visual system and the brain MRI as models for neurodegeneration. My fellowship was funded by the NMSS/American Brain Foundation Clinician Scientist Development Award. During fellowship, I also obtained pilot funding for several other projects and endeavors. I am starting a faculty position as Assistant Professor in Neurology at Washington University in St. Louis. I will continue to build on the knowledge and collaborative network that I started at Penn and hope to obtain my first mentored award in the very near future.
–Salim Chahin, MD, Fellow Class of 2014

Application Process

For those interested in our Adult Multiple Sclerosis Fellowship, please address and send a cover letter, curriculum vitae, three letters of recommendation and a professional photo to Jennifer Orthmann Murphy, MD, PhD: 

The application materials for our July 2023 Fellowship must be submitted in full by the deadline of January 15, 2022. Please note that we are reviewing applications on a rolling basis. 

For applicants interested in our Pediatric Multiple Sclerosis Fellowship, please send your materials to Sarah Hopkins, MD:

Multiple Sclerosis Faculty


Jennifer Orthmann Murphy, MD, PhD

Multiple Sclerosis Fellowship Director
Faculty Profile

Sarah Hopkins, MD, MSPH

Pediatric Multiple Sclerosis Fellowship Director

Amit Bar-Or, MD

President's Distinguished Professor
Multiple Sclerosis Division Chief
Faculty Profile

Brenda Banwell, MD

Chair, Department of Neurology at Children`s Hospital of Philadelphia
Faculty Profile

Joseph Berger, MD

Professor of Neurology 
Faculty Profile

Clyde Markowitz, MD

Associate Professor of Neurology

Dina Jacobs, MD

Associate Professor of Neurology
Faculty Profile


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Contact Information

Hospital of the University of Pennsylvania
Department of Neurology
3400 Spruce Street
3 W Gates
Philadelphia, PA 19104